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It starts with one forest in southern France
Les Landes de Gascogne. One kind of pine grows there, and it does not grow well anywhere else on earth. Its bark is where Pycnogenol comes from, and it is one of the most studied natural compounds in the world: more than 160 human clinical trials, over 10,000 people.4 Most botanical ingredients have nothing close to that behind them. And it has to be the real patented extract, because the research is on this one, not on generic pine bark off a shelf.